LOS ANGELES (Reuters) - Frank Sinatra, who sang, danced, loved and brawled his way through life while becoming one of the century's most beloved entertainers, has died aged 82, his spokeswoman said on Friday. Spokeswoman Susan Reynolds said Sinatra died of an acute heart attack in the emergency room of Cedars Sinai Medical Center in Los Angeles on Thursday. His fourth wife, Barbara, and his children Frank Jr., Tina, Robert and Nancy, as well as two grandchildren, were with the him when he died. "Frank Sinatra was the most influential vocalist of the 20th century ... Frank Sinatra was an incomparable personality whose impact will be felt for generations to come," said Reynolds. Known for his signature tune "My Way," Sinatra was affectionately called "Ol' Blue Eyes" by millions of fans. He had been in failing health for the last few months and had been hospitalized on several occasions in recent years. Reynolds said Sinatra's funeral would a private affair and it was his personal request that donations be made to the Barbara Sinatra Children's Center at the Eisenhower Medical Center in Rancho Mirage, California. He was the first pop singer to enthrall young teen-agers who flocked to his concerts in Manhattan in the 1940s, long before there was an Elvis Presley or the Beatles. From a career as a crooner, Sinatra became one of the world's most popular film stars and a presence that made millions around the world feel as if they knew him.